Research Services

Claims Substantiation/Product Use Studies

Our robust clinical research platform incorporates outcomes and photography to support claims substantiations for cosmetic, consumer products, over-the-counter and prescription drugs and devices for the skin. Types of claims typically substantiated by KGL include:

  • Dermatologist Tested
  • Clinically Tested
  • Allergy Tested
  • Hypoallergenic
  • Skin Types Desirability
  • Non-Irritating
  • Non-Stinging
  • Non-Photosensitizing
  • Formulated for Sensitive Skin
  • Reduction of Fine Lines / Wrinkles
  • Skin Brightening, Lightening or Smoothing
  • Cleanses & Moisturizes
  • Noncomedogenic / Non-Acnegenic
  • Anti-Inflammatory
  • Anti-Itch

Safety Patch Testing

KGL conducts a variety of repeat insult patch testing (RIPT) for assessing safety and tolerability for use on human skin. Many of which were developed by the founder of KGL, Dr. Albert M. Kligman. These types of studies remain the industry standard for new ingredient and product testing:

  • Allergenicity
  • Photosensitivity
  • Irritancy
  • Acnegenicity/Comedogenicity
  • Pruritus
  • Cell Turnover

Clinical Trials (Phase II – IV)

KGL’s large database and board-certified medical specialists makes us well suited for conducting phase II through IV clinical trials in diverse populations and study types

  • Aging Skin
  • Eczema/Atopic Dermatitis
  • Acne
  • Rosacea
  • Psoriasis 
  • Vitiligo
  • Warts /Molluscum
  • Aesthetic Devices and Injectables

Proof of Concept Studies

Small studies to demonstrate efficacy and/or safety prior to large scale testing are often useful starting points in commercial development. KGL has experience in designing and conducting proof of concept studies for a wide array of indications with both novel and customizable endpoints. Skin biopsy tissue acquisition provides analysis for:

  • Histology
  • Immunohistochemistry
  • DNA, RNA, Protein
  • Microbiology